Low Complement C3 Levels at Diagnosis of ANCA-Associated Glomerulonephritis, a Specific Subset of Patients to Target With Anti-C5aR Therapy?
Sign Up to like & getrecommendations! Published in 2021 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2021.08.026
Abstract: Low Complement C3 Levels at Diagnosis of ANCA-Associated Glomerulonephritis, a Specific Subset of Patients to Target With Anti-C5aR Therapy? In response to: Hypocomplementemia at Diagnosis of Pauciimmune Glomerulonephritis Is Associated with Advanced Histopathological Activity Index… read more here.
Keywords: anca associated; low complement; complement levels; levels diagnosis ... See more keywords
The clinical significance of low complement levels in patients with catastrophic antiphospholipid syndrome: A descriptive analysis of 73 patients from the “Catastrophic antiphospholipid syndrome registry”
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DOI: 10.1177/09612033221107583
Abstract: Objectives To explore the prevalence and clinical significance of low complement levels in patients with catastrophic antiphospholipid syndrome (CAPS). Methods We reviewed data from the “CAPS Registry” on C3 and/or C4 complement plasma protein levels… read more here.
Keywords: catastrophic antiphospholipid; patients catastrophic; complement; complement levels ... See more keywords
High serum C3 complement levels were associated with poor prognosis of angioimmunoblastic T-cell lymphoma (AITL)
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DOI: 10.1182/blood-2025-7158
Abstract: Background ： Angioimmunoblastic T-cell lymphoma (AITL), a distinct subtype of peripheral T-cell lymphoma (PTCL), presents with unique clinical features and poor prognosis. Primarily affecting elderly patients, AITL demonstrates aggressive disease progression characterized by systemic manifestations… read more here.
Keywords: cell lymphoma; analysis; prognosis; complement levels ... See more keywords
Association of Complement C3 with Clinical Deterioration Among Hospitalized Patients with COVID-19
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DOI: 10.2147/ijgm.s348519
Abstract: Background The role of the complement system in coronavirus disease 2019 (COVID-19) remains controversial. This study aimed to evaluate the relationship between serum complement C3 levels, clinical worsening, and risk of death in hospitalized patients… read more here.
Keywords: hospitalized patients; clinical worsening; complement; complement levels ... See more keywords
Correlation of Circulating Complement Levels with Clinical Characteristics of Patients with Diabetic Retinopathy
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DOI: 10.2147/ijgm.s483571
Abstract: Background Type 2 diabetes mellitus (T2DM) is associated with diabetic retinopathy (DR). The complement system maintains the normal physiologic microenvironment of the retina. The relationship between serum complement levels and clinical features of DR remains… read more here.
Keywords: patients t2dm; clinical characteristics; complement levels; diabetic retinopathy ... See more keywords
High plasma complement C4 levels as a novel predictor of clinical outcome in intracerebral hemorrhage
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2023.1103278
Abstract: Objective The complement cascade is activated and contributes to the brain injury after intracerebral hemorrhage (ICH). Complement component 4 (C4), an important component of complement cascade, has been associated with severity of neurological impairment that… read more here.
Keywords: complement; complement levels; clinical outcome; severity ... See more keywords
Low Preconception Complement Levels Are Associated with Adverse Pregnancy Outcomes in a Multicenter Study of 260 Pregnancies in 197 Women with Antiphospholipid Syndrome or Carriers of Antiphospholipid Antibodies
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DOI: 10.3390/biomedicines9060671
Abstract: Antiphospholipid antibodies (aPL) can induce fetal loss in experimental animal models. Human studies did find hypocomplementemia associated with pregnancy complications in patients with antiphospholipid syndrome (APS), but these results are not unanimously confirmed. To investigate… read more here.
Keywords: antiphospholipid syndrome; preconception; pregnancy; complement levels ... See more keywords
Megamonas funiformis, Plasma Zonulin, and Sodium Intake Affect C3 Complement Levels in Inactive Systemic Lupus Erythematosus
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DOI: 10.3390/nu15081999
Abstract: The etiology of systemic lupus erythematosus (SLE) remains unclear, with both genetic and environmental factors potentially contributing. This study aimed to explore the relationship among gut microbiota (GM), intestinal permeability, and food intake with inflammatory… read more here.
Keywords: megamonas funiformis; complement levels; intake; sodium intake ... See more keywords