Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling
Sign Up to like & getrecommendations! Published in 2017 at "Glia"
DOI: 10.1002/glia.23208
Abstract: The complement 3a receptor (C3aR1) participates in microglial signaling under pathological conditions and was recently shown to be activated by the neuropeptide TLQP‐21. We previously demonstrated that TLQP‐21 elicits hyperalgesia and contributes to nerve injury‐induced… read more here.
Keywords: tlqp; dorsal horn; complement receptor; horn microglia ... See more keywords
Complement receptor 3 mediates ruffle-like, actin-rich aggregates during phagocytosis of Leishmania infantum metacyclics.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2020.107968
Abstract: The parasitic protozoan Leishmania infantum resides primarily in macrophages throughout mammalian infection. Infection is initiated by deposition of the metacyclic promastigote into the dermis of a mammalian host by the sand fly vector. Promastigotes enter… read more here.
Keywords: phagocytosis; complement receptor; actin; ruffle like ... See more keywords
Human complement receptor type 1 (CR1) protein levels and genetic variants in chronic Chagas Disease
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18937-z
Abstract: Complement is an essential element in both innate and acquired immunity contributing to the immunopathogenesis of many disorders, including Chagas Disease (CD). Human complement receptor 1 (CR1) plays a role in the clearance of complement… read more here.
Keywords: human complement; cr1; chagas disease; complement receptor ... See more keywords
Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2300648120
Abstract: Autoantibodies against myelin oligodendrocyte glycoprotein (MOG) have recently been established to define a new disease entity, MOG-antibody-associated disease (MOGAD), which is clinically overlapping with multiple sclerosis. MOG-specific antibodies (Abs) from patients are pathogenic, but the… read more here.
Keywords: complement receptor; autoantibodies myelin; oligodendrocyte glycoprotein; myelin oligodendrocyte ... See more keywords
Anti-biofilm activity of antibody directed against surface antigen complement receptor 3-related protein-comparison of Candida albicans and Candida dubliniensis.
Sign Up to like & getrecommendations! Published in 2018 at "Pathogens and disease"
DOI: 10.1093/femspd/ftx127
Abstract: Candida albicans and C. dubliniensis are related yeasts that differ in the expression of virulence-associated proteins involved in adherence and biofilm development. CR3-RP (complement receptor 3-related protein) is one of the surface antigens expressed by… read more here.
Keywords: cr3; complement receptor; anti cr3; candida albicans ... See more keywords
Differential capacity for complement receptor‐mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oral Microbiology"
DOI: 10.1111/omi.12161
Abstract: The complement system plays a central role in immunity and inflammation, although certain pathogens can exploit complement to undermine protective immunity. In this context, the periodontal keystone pathogen Porphyromonas gingivalis was previously shown by our… read more here.
Keywords: receptor; porphyromonas gingivalis; complement receptor; gingivalis ... See more keywords
Staphylococcal protein Ecb impairs complement receptor-1 mediated recognition of opsonized bacteria
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0172675
Abstract: Staphyloccus aureus is a major human pathogen leading frequently to sepsis and soft tissue infections with abscesses. Multiple virulence factors including several immune modulating molecules contribute to its survival in the host. When S. aureus… read more here.
Keywords: recognition; c3b; protein ecb; complement receptor ... See more keywords
Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.00561
Abstract: Francisella tularensis is a remarkably infectious facultative intracellular bacterium of macrophages that causes tularemia. Early evasion of host immune responses contributes to the success of F. tularensis as a pathogen. F. tularensis entry into human… read more here.
Keywords: tularensis; cr3; complement receptor; ras gtpase ... See more keywords
Autotransporter-Mediated Display of Complement Receptor Ligands by Gram-Negative Bacteria Increases Antibody Responses and Limits Disease Severity
Sign Up to like & getrecommendations! Published in 2020 at "Pathogens"
DOI: 10.3390/pathogens9050375
Abstract: The targeting of immunogens/vaccines to specific immune cells is a promising approach for amplifying immune responses in the absence of exogenous adjuvants. However, the targeting approaches reported thus far require novel, labor-intensive reagents for each… read more here.
Keywords: complement receptor; gram negative; negative bacteria; autotransporter mediated ... See more keywords