Novel potential inhibitors of complement system and their roles in complement regulation and beyond.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular immunology"
DOI: 10.1016/j.molimm.2018.05.023
Abstract: The complement system resembles a double-edged sword since its activation can either benefit or harm the host. Thus, regulation of this system is of utmost importance and performed by several circulating and membrane-bound complement inhibitors.… read more here.
Keywords: complement inhibitors; complement regulation; complement system; regulation ... See more keywords
Additive Expression of hTBM on hCD46 Stable Cell Line Has Synergistic Effect on Complement Regulation
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000543735.57229.de
Abstract: Background Coagulation dysregulation and intravascular thrombosis during acute humoral xenograft rejection (AHXR) still remains the major obstacle in solid organ xenotransplantation. TBM or CD46 have been reported as an anti-coagulant or complement regulatory molecules and… read more here.
Keywords: hcd46; complement regulation; htbm hcd46; pig ... See more keywords