Evasion of the complement system by Leishmania through the uptake of factor H, a complement regulatory protein.
Sign Up to like & getrecommendations! Published in 2021 at "Acta tropica"
DOI: 10.1016/j.actatropica.2021.106152
Abstract: Escaping the complement system is an important step in the establishment of infections. Some pathogens have acquired the ability to inactivate the complement system to ensure successful infection. This has been observed in parasites from… read more here.
Keywords: complement regulatory; complement system; complement; factor ... See more keywords
Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood.2019003863
Abstract: The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies including anti-beta-2-glycoprotein-I (anti-β2GPI) that are considered central to APS pathogenesis. Based on animal studies showing a role of… read more here.
Keywords: 2gpi antibodies; anti 2gpi; complement regulatory; complement ... See more keywords
Effect of Heme Oxygenase-1 Depletion on Complement Regulatory Proteins Expression in the Rat
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox12010061
Abstract: Heme oxygenase has been implicated in the regulation of various immune responses including complement activation. Using a transgenic rat model of HO-1 depletion, the present study assessed the effect of HO-1 absence on the expression… read more here.
Keywords: complement; complement regulatory; heme oxygenase; regulatory proteins ... See more keywords