Articles with "complement sphingolipid" as a keyword



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Targeting the Complement–Sphingolipid System in COVID-19 and Gaucher Diseases: Evidence for a New Treatment Strategy

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232214340

Abstract: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-induced disease (COVID-19) and Gaucher disease (GD) exhibit upregulation of complement 5a (C5a) and its C5aR1 receptor, and excess synthesis of glycosphingolipids that lead to increased infiltration and activation of… read more here.

Keywords: complement; targeting complement; complement sphingolipid; covid gaucher ... See more keywords