Complete biosynthesis of the bisbenzylisoquinoline alkaloids guattegaumerine and berbamunine in yeast.
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DOI: 10.1073/pnas.2112520118
Abstract: Benzylisoquinoline alkaloids (BIAs) are a diverse class of medicinal plant natural products. Nearly 500 dimeric bisbenzylisoquinoline alkaloids (bisBIAs), produced by the coupling of two BIA monomers, have been characterized and display a range of pharmacological… read more here.
Keywords: bisbenzylisoquinoline alkaloids; yeast; complete biosynthesis; guattegaumerine berbamunine ... See more keywords