Obtaining Complete Human Proteomes.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of genomics and human genetics"
DOI: 10.1146/annurev-genom-112921-024948
Abstract: Proteins are the molecular effectors of the information encoded in the genome. Proteomics aims at understanding the molecular functions of proteins in their biological context. In contrast to transcriptomics and genomics, the study of proteomes… read more here.
Keywords: human proteomes; complete human; obtaining complete; biology ... See more keywords
Hypermetabolism in mice carrying a near-complete human chromosome 21
Sign Up to like & getrecommendations! Published in 2023 at "eLife"
DOI: 10.7554/elife.86023
Abstract: The consequences of aneuploidy have traditionally been studied in cell and animal models in which the extrachromosomal DNA is from the same species. Here, we explore a fundamental question concerning the impact of aneuploidy on… read more here.
Keywords: carrying near; hypermetabolism; near complete; complete human ... See more keywords