Iron deficiency without anemia is responsible for decreased left ventricular function and reduced mitochondrial complex I activity in a mouse model.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2018.02.021
Abstract: BACKGROUND Iron deficiency (ID), with or without anemia, is frequent in heart failure patients, and iron supplementation improves patient condition. However, the link between ID (independently of anemia) and cardiac function is poorly understood, but… read more here.
Keywords: complex activity; function; iron; mouse model ... See more keywords
Humanin directly protects cardiac mitochondria against dysfunction initiated by oxidative stress by decreasing complex I activity.
Sign Up to like & getrecommendations! Published in 2018 at "Mitochondrion"
DOI: 10.1016/j.mito.2017.08.001
Abstract: Humanin (HN) is an endogenous peptide that exerts cytoprotection against oxidative stress and apoptosis. We recently reported that Humanin analogue (HNG) pretreatment can reduce reactive oxygen species production in the heart subjected to ischemia/reperfusion (I/R)… read more here.
Keywords: oxidative stress; decreasing complex; stress; complex activity ... See more keywords
Microencapsulated pomegranate peel extract induces mitochondrial complex IV activity and prevents mitochondrial cristae alteration in brown adipose tissue in mice fed on a high-fat diet
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Nutrition"
DOI: 10.1017/s000711452000481x
Abstract: Abstract Pomegranate peel is an agro-industrial residue obtained after fruit processing with high total polyphenol (TP) content, making it an attractive by-product for its reuse. Pomegranate peel extract (PPE) and its bioactive compounds have shown… read more here.
Keywords: complex activity; mice; adipose tissue; hfd ... See more keywords
Abstract 3717: Defining the mechanism of ER receptor transcription complex activity and its effect on epigenetic modulations using super resolution microscopy
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3717
Abstract: Estrogen Receptor α (ERα) is expressed in ER+ breast cancers, one of the leading causes of death among women. Despite effectiveness of endocrine therapy, a significant number of patients experience resistance to these treatments. One… read more here.
Keywords: microscopy; super resolution; activity; complex activity ... See more keywords
Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types
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DOI: 10.7717/peerj.6500
Abstract: Abnormalities in mitochondrial function have previously been shown in chronic fatigue syndrome (CFS) patients, implying that mitochondrial dysfunction may contribute to the pathogenesis of disease. This study builds on previous work showing that mitochondrial respiratory… read more here.
Keywords: fatigue syndrome; complex activity; chronic fatigue; respiratory ... See more keywords