Particle Targeting in Complex Biological Media
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201700575
Abstract: Over the past few decades, nanoengineered particles have gained increasing interest for applications in the biomedical realm, including diagnosis, imaging, and therapy. When functionalized with targeting ligands, these particles have the potential to interact with… read more here.
Keywords: particle targeting; complex biological; biological media; protein corona ... See more keywords
Emerging Trends in Information-Driven Engineering of Complex Biological Systems.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201806898
Abstract: Synthetic biological systems are used for a myriad of applications, including tissue engineered constructs for in vivo use and microengineered devices for in vitro testing. Recent advances in engineering complex biological systems have been fueled… read more here.
Keywords: information; emerging trends; biological systems; engineering complex ... See more keywords
Bionic Engineered Protein Coating Boosting Anti‐Biofouling in Complex Biological Fluids
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202208824
Abstract: Implantable medical devices have been widely applied in diagnostics, therapeutics, organ restoration, and other biomedical areas, but often suffer from dysfunction and infections due to irreversible biofouling. Inspired by the self‐defensive “vine‐thorn” structure of climbing… read more here.
Keywords: biofouling; complex biological; engineered protein; surface ... See more keywords
Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6850-3_18
Abstract: Proteolytic Activity Matrix Analysis (PrAMA) is a method for simultaneously determining the activities of specific Matrix Metalloproteinases (MMPs) and A Disintegrin and Metalloproteinases (ADAMs) in complex biological samples. In mixtures of unknown proteases, PrAMA infers… read more here.
Keywords: proteolytic activity; activity matrix; biological samples; complex biological ... See more keywords
The use of hydrocolloids in physical modelling of complex biological matrices
Sign Up to like & getrecommendations! Published in 2017 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2016.09.033
Abstract: Hydrated biological matrices are widely distributed in nature, and the understanding of the complexity and functionality of such systems has increased quite dramatically over the recent years. A picture evolves where such systems are considered… read more here.
Keywords: physical modelling; hydrocolloids physical; complex biological; biological matrices ... See more keywords
Structural and dynamics studies of the TetR family protein, CprB from Streptomyces coelicolor in complex with its biological operator sequence.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of structural biology"
DOI: 10.1016/j.jsb.2017.03.006
Abstract: In Streptomycetes, tetracycline repressor family of transcription regulators (TetR-FTRs) controls various biological processes including antibiotic biosynthesis, cellular morphology and innate resistance. Here, we focus on understanding the structural basis of transcription regulation by CprB, a… read more here.
Keywords: cprb; operator sequence; tetr ftrs; dna ... See more keywords
Metabolomics Peak Analysis Computational Tool (MPACT): An Advanced Informatics Tool for Metabolomics and Data Visualization of Molecules from Complex Biological Samples.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c04632
Abstract: Untargeted metabolomics is a powerful tool for investigating chemistry of complex biological systems, but its utility is compromised by the presence of uninformative features and the limited efficiency of currently available prioritization tools. More effective… read more here.
Keywords: tool; complex biological; mpact; chemistry ... See more keywords
Electrochemical Aptasensor for Ultralow Fouling Cancer Cell Quantification in Complex Biological Media Based on Designed Branched Peptides.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b01129
Abstract: The rapid, convenient, and selective assaying of clinical targets directly in complex biological media brings with it the potential to revolutionize diagnostics. One major hurdle to impact is retention of selectivity and a tight control… read more here.
Keywords: branched peptides; complex biological; biological media; designed branched ... See more keywords
Designed three-in-one peptides with anchoring, antifouling and recognizing capabilities for highly sensitive and low fouling electrochemical sensing in complex biological media.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b05299
Abstract: Nonspecific adsorption is of great concern for electrochemical biosensors performing in complex biological media, and various antifouling materials have been introduced into the sensing interfaces to improve the antifouling capability of different biosensors. However, for… read more here.
Keywords: part; anchoring antifouling; complex biological; designed three ... See more keywords
Ti(IV) and the Siderophore Desferrioxamine B: A Tight Complex Has Biological and Environmental Implications.
Sign Up to like & getrecommendations! Published in 2017 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.6b02399
Abstract: The siderophore desferrioxamine B (DFOB) binds Ti(IV) tightly and precludes its hydrolytic precipitation under biologically and environmentally relevant conditions. This interaction of DFOB with Ti(IV) is investigated by using spectro-potentiometric and spectro-photometric titrations, mass spectrometry,… read more here.
Keywords: tight complex; environmental implications; dfob; complex biological ... See more keywords
Self-Propelled Janus Mesoporous Micromotor for Enhanced MicroRNA Capture and Amplified Detection in Complex Biological Samples.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c10437
Abstract: The slow mass transport of the target molecule essentially limits the biosensing performance. Here, we report a Janus mesoporous microsphere/Pt-based (meso-MS/Pt) nanostructure with greatly enhanced target transport and accelerated recognition process for microRNA (miRNA) amplified… read more here.
Keywords: janus mesoporous; amplified detection; micromotor; biological samples ... See more keywords