MLL1 Complex Is a Critical Regulator of Fetal Hemoglobin Repression
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-199305
Abstract: Increasing fetal-type hemoglobin (HbF) expression in adult erythroid cells represents a promising strategy for treating β-globinopathies including sickle cell disease and β-thalassemia. However, the mechanisms responsible for the repression of HbF expression in adult erythroid… read more here.
Keywords: bcl11a; complex critical; mll1 complex; expression ... See more keywords
The mARS complex: a critical mediator of immune regulation and homeostasis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1423510
Abstract: Over the course of evolution, many proteins have undergone adaptive structural changes to meet the increasing homeostatic regulatory demands of multicellularity. Aminoacyl tRNA synthetases (aaRS), enzymes that catalyze the attachment of each amino acid to… read more here.
Keywords: immune regulation; mars complexes; homeostasis; complex critical ... See more keywords
Applications of Biotechnology to the Craniofacial Complex: A Critical Review
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9110640
Abstract: Background: Biotechnology shows a promising future in bridging the gap between biomedical basic sciences and clinical craniofacial practice. The purpose of the present review is to investigate the applications of biotechnology in the craniofacial complex.… read more here.
Keywords: applications biotechnology; critical review; biotechnology craniofacial; review ... See more keywords