Can 'easy' chemistry produce complex, diverse, and novel molecules?
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DOI: 10.1016/j.drudis.2020.09.027
Abstract: Statements, such as 'you need to break free from amide-formations to improve molecular properties' and 'novel chemistry leads to novel biology' are frequently encountered in the medicinal chemistry community. To verify whether truth lies in… read more here.
Keywords: easy chemistry; complex diverse; chemistry; novel molecules ... See more keywords
The Complex and Diverse Genetic Architecture of the Absence of Horns (Polledness) in Domestic Ruminants, including Goats and Sheep
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DOI: 10.3390/genes13050832
Abstract: Horns are the most obvious common feature of Bovidae. The naturally occurring absence of horns in these species, also known as polledness, is of surprisingly heterogeneous nature, although they are Mendelian traits. This review compares… read more here.
Keywords: polledness domestic; complex diverse; diverse genetic; genetic architecture ... See more keywords