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   Articles with "complex gene" as a keyword



What can we learn when fitting a simple telegraph model to a complex gene expression model?

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recommendations! Published in 2024 at "PLOS Computational Biology"

DOI: 10.1101/2023.03.09.532005

Abstract: In experiments, the distributions of mRNA or protein numbers in single cells are often fitted to the random telegraph model which includes synthesis and decay of mRNA or protein, and switching of the gene between… read more here.

Keywords: complex gene; telegraph model; gene; model ... See more keywords
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Genetic variants in R-Spondin/RNF43 complex and gene expression levels to predict efficacy of cetuximab (cet) in patients (pts) with metastatic colorectal cancer (mCRC): Data from the FIRE-3 phase III trial.

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recommendations! Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.4_suppl.190

Abstract: 190Background: Wnt signaling deregulation is a primary driver of colorectal carcinogenesis. RNF43 is a key suppressor of Wnt activation while R-Spodin inhibits RNF43 activity. RNF43 mutations are a... read more here.

Keywords: complex gene; rnf43 complex; variants spondin; genetic variants ... See more keywords

Estrogen/ERĪ± signaling axis participates in osteoblast maturation via upregulating chromosomal and mitochondrial complex gene expressions

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recommendations! Published in 2018 at "Oncotarget"

DOI: 10.18632/oncotarget.23453

Abstract: Estrogen deficiency usually leads to bone loss and osteoporosis in postmenopausal women. Osteoblasts play crucial roles in bone formation. However, osteoblast functions are influenced by mitochondrial bioenergetic conditions. In this study, we investigated the roles… read more here.

Keywords: complex gene; signaling axis; mitochondrial complex; chromosomal mitochondrial ... See more keywords

A Complex Gene Network Mediated by Ethylene Signal Transduction TFs Defines the Flower Induction and Differentiation in Olea europaea L.

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recommendations! Published in 2021 at "Genes"

DOI: 10.3390/genes12040545

Abstract: The olive tree (Olea europaea L.) is a typical Mediterranean crop, important for olive and oil production. The high tendency to bear fruits in an uneven manner, defined as irregular or alternate bearing, results in… read more here.

Keywords: induction differentiation; complex gene; differentiation; olea europaea ... See more keywords