Increased Cysteine Sulfonation of the Hydrophilic Domain of Complex I Mediates Mitochondrial Dysfunction in the Post-ischemic Heart
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DOI: 10.1016/j.freeradbiomed.2017.10.170
Abstract: A serious consequence of ischemia-reperfusion injury (I/R) is oxidative damage leading to mitochondrial dysfunction. Such I/R-induced mitochondrial dysfunction is observed as impaired state 3 respiration, decreased ATP generation, and overproduction of O2. The cascading ROS… read more here.
Keywords: complex mediates; post ischemic; dysfunction; sulfonation ... See more keywords