Patent Cliffs in the Era of Complex Therapies and Biologics
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutical Medicine"
DOI: 10.1007/s40290-020-00348-7
Abstract: The rise of new product classes such as biologics and complex molecules over the past two decades have brought to light some of the unique market dynamics that such products face. While we have seen… read more here.
Keywords: complex molecules; product; product classes; biologics complex ... See more keywords
A Rigorous Method for Identifying a One-Dimensional Reaction Coordinate in Complex Molecules.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.2c00132
Abstract: Understanding the mechanism of functional protein dynamics is critical to understanding protein functions. Reaction coordinate (RC) is a central topic in protein dynamics, and the grail is to find the one-dimensional RC (1D-RC) that can… read more here.
Keywords: method; complex molecules; reaction coordinate; reaction ... See more keywords