Backbone chemical shift assignments of the glycine cleavage complex H protein of Escherichia coli
Sign Up to like & getrecommendations! Published in 2018 at "Biomolecular NMR Assignments"
DOI: 10.1007/s12104-018-9801-z
Abstract: Glycine cleavage complex H protein (GcvH) is one of the four components that form the glycine cleavage complex (GCS), essential for the synthesis of C1 (one-carbon units) for cell metabolism, by the oxidative cleavage of… read more here.
Keywords: cleavage; escherichia coli; complex protein; glycine cleavage ... See more keywords
Characterization and Expression Pattern Analysis of the T-Complex Protein-1 Zeta Subunit in Musca domestica L (Diptera)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Insect Science"
DOI: 10.1093/jisesa/iex063
Abstract: Abstract Chaperonins, belonging to the T-complex protein-1 (TCP-1) family, assist in the correct folding of nascent and misfolded proteins. It is well-known that in mammals, the zeta subunit of the TCP-1 complex (TCP-1ζ) plays a… read more here.
Keywords: mdtcp; analysis; complex protein; zeta subunit ... See more keywords
Structures of Ric-8B in complex with Gα protein folding clients reveal isoform specificity mechanisms.
Sign Up to like & getrecommendations! Published in 2023 at "Structure"
DOI: 10.2139/ssrn.4254228
Abstract: Mammalian Ric-8 proteins act as chaperones to regulate the cellular abundance of heterotrimeric G protein α subunits. The Ric-8A isoform chaperones Gαi/o, Gα12/13, and Gαq/11 subunits, while Ric-8B acts on Gαs/olf subunits. Here, we determined… read more here.
Keywords: protein folding; structures ric; ric complex; complex protein ... See more keywords
The role of ligand-binding assay and LC-MS in the bioanalysis of complex protein and oligonucleotide therapeutics.
Sign Up to like & getrecommendations! Published in 2021 at "Bioanalysis"
DOI: 10.4155/bio-2021-0009
Abstract: Ligand-binding assay (LBA) and LC-MS have been the preferred bioanalytical techniques for the quantitation and biotransformation assessment of various therapeutic modalities. This review provides an overview of the applications of LBA, LC-MS/MS and LC-HRMS for… read more here.
Keywords: binding assay; bioanalysis; oligonucleotide therapeutics; complex protein ... See more keywords
T-complex protein 1 subunit zeta-2 (CCT6B) deficiency induces murine teratospermia
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DOI: 10.7717/peerj.11545
Abstract: Background The CCT complex is an important mediator of microtubule assembly and intracellular protein folding. Owing to its high expression in spermatids, CCT knockdown can disrupt spermatogenesis. In the present report, we therefore evaluated the… read more here.
Keywords: protein; cct complex; protein subunit; subunit zeta ... See more keywords