Mechanistically Guided Workflow for Relating Complex Reactive Site Topologies to Catalyst Performance in C-H Functionalization Reactions.
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DOI: 10.1021/jacs.1c12198
Abstract: Leveraging congested catalyst scaffolds has emerged as a key strategy for altering innate substrate site-selectivity profiles in C-H functionalization reactions. Similar to enzyme active sites, optimal small molecule catalysts often feature reactive cavities tailored for… read more here.
Keywords: reactive site; site selectivity; complex reactive; functionalization ... See more keywords