A model of DNA unwinding dynamics by the RecBCD complex and its regulation by Chi recognition.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of theoretical biology"
DOI: 10.1016/j.jtbi.2018.04.014
Abstract: The Escherichia coli RecBCD enzyme is a heterotrimeric helicase-nuclease complex responsible for processing of double-stranded DNA breaks for repair by homologous recombination. It is a highly processive, duplex unwinding and degrading motor, with its activities… read more here.
Keywords: chi; model; complex regulation; recbcd complex ... See more keywords
The private security complex and its regulation in Africa: select examples from the continent
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Comparative and Applied Criminal Justice"
DOI: 10.1080/01924036.2017.1364280
Abstract: ABSTRACT This article aims to provide an overview of the primary trends and developments of the domestic private security industry in select countries in Africa, while also further reflecting on a selection of operational challenges… read more here.
Keywords: private security; security; complex regulation; regulation africa ... See more keywords
The complex regulation of Slo1 potassium channels from a structural perspective
Sign Up to like & getrecommendations! Published in 2024 at "Biological Chemistry"
DOI: 10.1515/hsz-2024-0037
Abstract: Abstract Fast and regulated potassium efflux by Slo1 channels is crucial in many tissues in animals including neurons, the kidney and smooth muscle. During the last decade, structures have revealed many details about the gating… read more here.
Keywords: regulation slo1; complex regulation; slo1 potassium; potassium ... See more keywords
Adenylyl cyclase isoforms 5 and 6 in the cardiovascular system: complex regulation and divergent roles
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2024.1370506
Abstract: Adenylyl cyclases (ACs) are crucial effector enzymes that transduce divergent signals from upstream receptor pathways and are responsible for catalyzing the conversion of ATP to cAMP. The ten AC isoforms are categorized into four main… read more here.
Keywords: ac5 ac6; cardiovascular system; complex regulation; ac6 ... See more keywords
Shedding Light on the Complex Regulation of FGF23
Sign Up to like & getrecommendations! Published in 2022 at "Metabolites"
DOI: 10.3390/metabo12050401
Abstract: Early research has suggested a rather straightforward relation between phosphate exposure, increased serum FGF23 (Fibroblast Growth Factor 23) concentrations and clinical endpoints. Unsurprisingly, however, subsequent studies have revealed a much more complex interplay between autocrine… read more here.
Keywords: regulation fgf23; complex regulation; fgf23; light complex ... See more keywords