An iron(iii) complex selectively mediated cancer cell death: crystal structure, DNA targeting and in vitro antitumor activities
Sign Up to like & getrecommendations! Published in 2019 at "Inorganic Chemistry Frontiers"
DOI: 10.1039/c9qi00030e
Abstract: Three new iron(iii) complexes were prepared, and complex 3 exhibited a 14-fold higher selectivity index for HeLa vs. LO2 normal cells than cisplatin. read more here.
Keywords: iii; selectively mediated; iron iii; mediated cancer ... See more keywords
Novel Organoruthenium(II) Complex C1 Selectively Inhibits Butyrylcholinesterase without Side Effects on Neuromuscular Transmission
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032681
Abstract: Enzyme butyrylcholinesterase (BChE) shows increased activity in some brain regions after progression of Alzheimer’s disease and is therefore one of the therapeutic targets for symptomatic treatment of this neurodegenerative disorder. The organoruthenium(II) complex [(η6-p-cymene)Ru(II)(1-hydroxy-3-methoxypyridine-2(1H)-thionato)pta]PF6 (C1)… read more here.
Keywords: effect; organoruthenium complex; neuromuscular transmission; complex selectively ... See more keywords