CtD strategy to construct stereochemically complex and structurally diverse compounds from griseofulvin.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc04007c
Abstract: The Complexity to Diversity (CtD) strategy, a strategy for the synthesis of stereochemically complex and structurally diverse small molecules from natural products using ring-distortion reactions, was applied in the synthesis of a 47-member compound collection… read more here.
Keywords: complex structurally; stereochemically complex; ctd strategy; structurally diverse ... See more keywords
Crystal structures of bacterial small multidrug resistance transporter EmrE in complex with structurally diverse substrates
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DOI: 10.1101/2022.01.11.475788
Abstract: Proteins from the bacterial small multidrug resistance (SMR) family are proton-coupled exporters of diverse antiseptics and antimicrobials, including polyaromatic cations and quaternary ammonium compounds. The transport mechanism of the Escherichia coli transporter, EmrE, has been… read more here.
Keywords: bacterial small; multidrug resistance; small multidrug; complex structurally ... See more keywords