Therapeutic potential of Mediator complex subunits in metabolic diseases.
Sign Up to like & getrecommendations! Published in 2018 at "Biochimie"
DOI: 10.1016/j.biochi.2017.10.012
Abstract: The multisubunit Mediator is an evolutionary conserved transcriptional coregulatory complex in eukaryotes. It is needed for the transcriptional regulation of gene expression in general as well as in a gene specific manner. Mediator complex subunits… read more here.
Keywords: transcription; mediator; metabolic diseases; mediator complex ... See more keywords
Roles for Mitochondrial Complex I Subunits in Regulating Synaptic Transmission and Growth
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.846425
Abstract: To identify conserved components of synapse function that are also associated with human diseases, we conducted a genetic screen. We used the Drosophila melanogaster neuromuscular junction (NMJ) as a model. We employed RNA interference (RNAi)… read more here.
Keywords: mitochondrial complex; function; mci; complex subunits ... See more keywords
Cloning and Organelle Expression of Bamboo Mitochondrial Complex I Subunits Nad1, Nad2, Nad4, and Nad5 in the Yeast Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23074054
Abstract: Mitochondrial respiratory complex I catalyzes electron transfer from NADH to ubiquinone and pumps protons from the matrix into the intermembrane space. In particular, the complex I subunits Nad1, Nad2, Nad4, and Nad5, which are encoded… read more here.
Keywords: complex subunits; nad2 nad4; nad1 nad2; nad4 nad5 ... See more keywords