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Published in 2020 at "Advanced materials"
DOI: 10.1002/adma.202005030
Abstract: Engineering complex tissues represents an extraordinary challenge and, to date, there have been few strategies developed that can easily recapitulate native-like cell and biofactor gradients in 3D materials. This is true despite the fact that…
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Keywords:
magneto driven;
complex tissues;
engineering complex;
diamagnetic objects ... See more keywords
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Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa205
Abstract: SUMMARY We develop a fully unsupervised deconvolution method to dissect complex tissues into molecularly distinctive tissue or cell subtypes based on bulk expression profiles. We implement an R package, deconvolution by Convex Analysis of Mixtures…
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Keywords:
package;
complex tissues;
fully unsupervised;
tissue ... See more keywords
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Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa312
Abstract: Abstract Multiplex single-molecule fluorescent in situ hybridization (smFISH) is a powerful method for validating RNA sequencing and emerging spatial transcriptomic data, but quantification remains a computational challenge. We present a framework for generating and analyzing…
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Keywords:
fluorescent situ;
single molecule;
multiplex single;
complex tissues ... See more keywords
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Published in 2022 at "Journal of Biomedical Optics"
DOI: 10.1117/1.jbo.27.8.083014
Abstract: Abstract. Significance: Rapid advances in biophotonics techniques require quantitative, model-based computational approaches to obtain functional and structural information from increasingly complex and multiscaled anatomies. The lack of efficient tools to accurately model tissue structures and…
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Keywords:
open source;
source;
software;
three dimensional ... See more keywords