A mixed-valence biotinylated Cu(I/II) complex for tumor-targeted chemodynamic therapy accompanied with GSH depletion
Sign Up to like & getrecommendations! Published in 2023 at "Inorganic Chemistry Frontiers"
DOI: 10.1039/d3qi00254c
Abstract: Chemodynamic therapy (CDT), in which highly toxic hydroxyl radicals (•OH) could be triggered by Fenton or Fenton-like reaction to kill cancer cells, has been emerged recently. Compared to traditional CDT... read more here.
Keywords: biotinylated complex; valence biotinylated; therapy; complex tumor ... See more keywords
Abstract PO010: Engineering T cells to enhance 3D migration through mechanically and structurally complex tumor microenvironments
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Research"
DOI: 10.1158/1538-7445.tme21-po010
Abstract: While chemical signals play a strong role in drawing T cells into solid tumors, the physical features of the stroma, such as architecture and mechanics, also strongly influence T cell infiltration as well as their… read more here.
Keywords: complex tumor; tumor microenvironments; engineering; tumor ... See more keywords
The Complex Tumor Microenvironment in Ovarian Cancer: Therapeutic Challenges and Opportunities
Sign Up to like & getrecommendations! Published in 2024 at "Current Oncology"
DOI: 10.3390/curroncol31070283
Abstract: The tumor microenvironment (TME) in ovarian cancer (OC) has much greater complexity than previously understood. In response to aggressive pro-angiogenic stimulus, blood vessels form rapidly and are dysfunctional, resulting in poor perfusion, tissue hypoxia, and… read more here.
Keywords: complex tumor; cancer; tumor microenvironment; tumor ... See more keywords
Complex Tumor Spheroid Formation and One-Step Cancer-Associated Fibroblasts Purification from Hepatocellular Carcinoma Tissue Promoted by Inorganic Surface Topography
Sign Up to like & getrecommendations! Published in 2021 at "Nanomaterials"
DOI: 10.3390/nano11123233
Abstract: In vitro cell models play important roles as testbeds for toxicity studies, drug development, or as replacements in animal experiments. In particular, complex tumor models such as hepatocellular carcinoma (HCC) are needed to predict drug… read more here.
Keywords: tumor; tissue; hepatocellular carcinoma; topography ... See more keywords