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   Articles with "complex vitro" as a keyword



3D bioprinting of E. coli MG1655 biofilms on human lung epithelial cells for building complex in vitro infection models.

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recommendations! Published in 2023 at "Biofabrication"

DOI: 10.1088/1758-5090/acd95e

Abstract: Biofilm-associated infections are causing over half a million deaths each year, raising the requirement for innovative therapeutic approaches. For developing novel therapeutics against bacterial biofilm infections, complex in vitro models that allow to study drug… read more here.

Keywords: vitro; infection models; vitro infection; coli mg1655 ... See more keywords

Complex in vitro models positioned for impact to drug testing in pharma: a review

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recommendations! Published in 2024 at "Biofabrication"

DOI: 10.1088/1758-5090/ad6933

Abstract: Recent years have seen the creation and popularization of various complex in vitro models (CIVMs), such as organoids and organs-on-chip, as a technology with the potential to reduce animal usage in pharma while also enhancing… read more here.

Keywords: drug; complex vitro; model; vitro models ... See more keywords

Complex In Vitro Model Characterization for Context of Use in Toxicologic Pathology: Use Cases by Collaborative Teams of Biologists, Bioengineers, and Pathologists

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recommendations! Published in 2024 at "Toxicologic Pathology"

DOI: 10.1177/01926233241253811

Abstract: Complex in vitro models (CIVMs) offer the potential to increase the clinical relevance of preclinical efficacy and toxicity assessments and reduce the reliance on animals in drug development. The European Society of Toxicologic Pathology (ESTP)… read more here.

Keywords: use; toxicologic pathology; pathology; complex vitro ... See more keywords

Human-based complex in vitro models: their promise and potential for rare disease therapeutics

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recommendations! Published in 2025 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2025.1526306

Abstract: Rare diseases affect a small percentage of an individual country’s population; however, with over 7,000 in total, rare diseases represent a significant disease burden impacting up to 10% of the world’s population. Despite this, there… read more here.

Keywords: disease; rare diseases; rare disease; complex vitro ... See more keywords