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   Articles with "complexes dna" as a keyword



Phenanthrene Appending Ruthenium Complexes: DNA Binding, Molecular Docking, TDDFT Calculation, and Photocytoxicity In Vitro

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recommendations! Published in 2024 at "Applied Organometallic Chemistry"

DOI: 10.1002/aoc.7735

Abstract: Photodynamic therapy (PDT) has been an effective tumor treatment to reduce the side effects of chemotherapy. Herein, we described the synthesis of two Ru (II) complexes by introducing a phenanthrene unit and their photocytotoxicity. Ru1… read more here.

Keywords: phenanthrene appending; phenanthrene; appending ruthenium; complexes dna ... See more keywords

DNA interaction, docking, molecular modelling and biological studies of o-Vanillin derived Schiff base metal complexes

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recommendations! Published in 2019 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2019.02.093

Abstract: Abstract In the present studies, [Cu(ABOVL)]1, [Co(ABOVL)]2, [Cr (ABOVL)]3, and [Zn (ABOVL)]4 complexes were prepared where ABOVL is the condensation product of 2-hydroxy-3-methoxybenzaldehyde (o-Vanillin) and (2-aminophenyl)methanol (2-aminobenzylalcohol). To characterize ABOVL and its metal complexes standard… read more here.

Keywords: molecular modelling; abovl abovl; dna; metal complexes ... See more keywords

Structurally different mono-, bi- and trinuclear Pd(II) complexes and their DNA/protein interaction, DNA cleavage, and anti-oxidant, anti-microbial and cytotoxic studies

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recommendations! Published in 2017 at "New Journal of Chemistry"

DOI: 10.1039/c7nj01556a

Abstract: A series of new structurally different Pd(II) complexes was obtained by the reactions between K-2PdCl4], 3-methoxysalicylaldehyde-4(N)-substituted thiosemicarbazone H2L1-H2L4] and bis(diphenylphosphino) ethane dppe]. All the complexes were characterized by using various spectral techniques (IR, electronic, H-1-NMR… read more here.

Keywords: dna; structurally different; anti oxidant; different mono ... See more keywords

In vitro studies on the selective cytotoxic effect of luminescent Ru(II)-p-cymene complexes of imidazo-pyridine and imidazo quinoline ligands.

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recommendations! Published in 2022 at "Dalton transactions"

DOI: 10.1039/d2dt02237k

Abstract: In recent years, Ru(II) complexes have gained high importance in medicinal chemistry due to their significant anti-cancer activities, which are directly related to their DNA binding ability. In this report, the chemistry and cytotoxicity of… read more here.

Keywords: vitro studies; effect; chemistry; studies selective ... See more keywords

Highly sensitive mapping of in vitro type II topoisomerase DNA cleavage sites with SHAN-seq.

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recommendations! Published in 2024 at "Nucleic acids research"

DOI: 10.1093/nar/gkae638

Abstract: Type II topoisomerases (topos) are a ubiquitous and essential class of enzymes that form transient enzyme-bound double-stranded breaks on DNA called cleavage complexes. The location and frequency of these cleavage complexes on DNA is important… read more here.

Keywords: complexes dna; cleavage complexes; type; topoisomerase ... See more keywords