Complexes of N- and O-Donor Ligands as Potential Urease Inhibitors
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DOI: 10.1021/acsomega.0c01089
Abstract: We report five new transition-metal complexes that inhibit the urease enzyme. Barbituric acid (BTA), thiobarbituric acid (TBA), isoniazid (INZ), and nicotinamide (NCA) ligands were employed in complexation reactions. The resulting complexes were characterized using a… read more here.
Keywords: donor ligands; potential urease; h2o; complexes donor ... See more keywords
Heterometallic Cu(II)-M(II) (M = Mg, Ca and Sr) complexes with a N,O-donor ligand in situ generated from topiroxostat
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Coordination Chemistry"
DOI: 10.1080/00958972.2020.1734189
Abstract: Abstract By introducing alkaline-earth metal ions (Mg2+, Ca2+, and Sr2+) as structure-directing agents, three new heterometallic complexes, Mg(H2O)6·[Cu2Mg(L)4(H2O)4]·4H2O (1), [CuCa(L)2(H2O)4]n (2) and [CuSr(L)2(H2O)4]n (3) [H2L = 4-(3-(pyridine-4-yl)-1H-1,2,4-triazol-5-yl)picolinic acid], have been synthesized under hydrothermal conditions and… read more here.
Keywords: donor ligand; heterometallic complexes; situ generated; h2o ... See more keywords
Selective Cytotoxicity of Complexes with N,N,N-Donor Dipodal Ligand in Tumor Cells
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DOI: 10.3390/ijms22041802
Abstract: The present article demonstrates selective cytotoxicity against cancer cells of the complexes [Co(LD)2]I2∙CH3OH (1), [CoLD(NCS)2] (2) and [VOLD(NCS)2]∙C6H5CH3 (3) containing the dipodal tridentate ligand LD = N,N-bis(3,5-dimethylpyrazol-1-ylmethyl)amine), formed in situ. All tested complexes expressed greater… read more here.
Keywords: selective cytotoxicity; cytotoxicity complexes; complexes donor; cancer cells ... See more keywords