Diverse signaling mechanisms of mTOR complexes: mTORC1 and mTORC2 in forming a formidable relationship.
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DOI: 10.1016/j.jbior.2019.03.003
Abstract: Activation of Mechanistic target of rapamycin (mTOR) signaling plays a crucial role in tumorigenesis of numerous malignancies including glioblastoma (GB). The Canonical PI3K/Akt/mTOR signaling cascade is commonly upregulated due to loss of the tumor suppressorm… read more here.
Keywords: complexes mtorc1; mtor; activity; mtorc1 mtorc2 ... See more keywords