Physicochemical characteristics of the complexes of simvastatin and atorvastatin calcium with hydroxypropyl-β-cyclodextrin produced by mechanochemical activation
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DOI: 10.1016/j.jddst.2018.05.018
Abstract: Abstract In the present work, inclusion complexes of simvastatin (SIM), atorvastatin calcium (ATV) with hydroxypropyl-β-cyclodextrin (HP-β-CD) have been prepared using mechanochemistry technique to improve solubility of the two drugs and enhance their oral bioavailability. The… read more here.
Keywords: complexes simvastatin; hydroxypropyl cyclodextrin; atv; atorvastatin calcium ... See more keywords