FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I–induced DNA breakage and transcriptional stress
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DOI: 10.26508/lsa.201800222
Abstract: This work shows that the ALS-associated protein FUS is a component of the cellular response to transcriptional stress induced by topoisomerase I–induced DNA breakage, thereby accumulating at sites of nucleolar rRNA synthesis. FUS (fused in… read more here.
Keywords: induced dna; component cellular; dna breakage; cellular response ... See more keywords
Nrf2, an essential component of cellular stress response, as a potential target of hormetic phytochemicals
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DOI: 10.38212/2224-6614.2141
Abstract: Living organisms have evolved ubiquitous mechanisms to manage a vast multitude of stressors and noxious conditions. Although Nrf2 mainly plays a major role in cellular antioxidant defense, results from recent studies have highlighted its ubiquitous… read more here.
Keywords: essential component; component cellular; nrf2 essential; target ... See more keywords