TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
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DOI: 10.1038/s41467-018-06699-9
Abstract: Chromosome 17q gains are almost invariably present in high-risk neuroblastoma cases. Here, we perform an integrative epigenomics search for dosage-sensitive transcription factors on 17q marked by H3K27ac defined super-enhancers and identify TBX2 as top candidate… read more here.
Keywords: dream; circuitry component; regulatory circuitry; component enhancing ... See more keywords