Development of dual-component protein microparticles in all-aqueous systems for biomedical applications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry B"
DOI: 10.1039/c8tb03074j
Abstract: Protein microparticles assisted by an emulsion droplet template have shown great promise in drug/cell delivery and tissue engineering, as well as diagnosis and treatment of diseases. read more here.
Keywords: microparticles aqueous; development dual; component protein; dual component ... See more keywords
Aging can transform single-component protein condensates into multiphase architectures
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2119800119
Abstract: Significance Biomolecular condensates are highly diverse systems spanning not only homogeneous liquid droplets but also gels, glasses, and even multiphase architectures that contain various coexisting liquid-like and/or gel-like inner phases. Multiphase architectures form when the… read more here.
Keywords: transform single; aging transform; component protein; single component ... See more keywords
A two-component protein condensate of the EGFR cytoplasmic tail and Grb2 regulates Ras activation by SOS at the membrane
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2122531119
Abstract: Significance Two-dimensional condensates of proteins on the membrane surface, driven by tyrosine phosphorylation, are beginning to emerge as important players in signal transduction. This work describes discovery of a protein condensation phase transition of EGFR… read more here.
Keywords: grb2; protein condensate; component protein; two component ... See more keywords
Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1015840
Abstract: Nanoparticle vaccines usually prime stronger immune responses than soluble antigens. Within this class of subunit vaccines, the recent development of computationally designed self-assembling two-component protein nanoparticle scaffolds provides a powerful and versatile platform for displaying… read more here.
Keywords: nanoparticle; component protein; protein nanoparticle; two component ... See more keywords