Photoinduced Copper‐Catalyzed Three‐Component Radical Carboamination of Styrene Derivatives
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DOI: 10.1002/cctc.202401234
Abstract: The catalytic three‐component radical carboamination of alkenes has recently emerged as an alternative and robust platform for the rapid construction of diverse and valuable amines. Despite great advances in this field, new methods that enable… read more here.
Keywords: catalyzed three; radical carboamination; three component; copper catalyzed ... See more keywords
Three‐Component Radical Iodonitration of 1,6‐Enynes to Access Iodo‐ and Nitro‐ Di‐Functionalized 4‐Enyl‐2‐Pyrrolidones
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DOI: 10.1002/jhet.70078
Abstract: Herein, we report a three‐component radical cascade cyclization reaction for the synthesis of iodo‐ and nitro‐di‐functionalized 4‐enyl‐2‐pyrrolidones with 1,6‐enynes under metal‐free and catalyst‐free conditions. In this reaction, the (Z) configuration products with high stereoselectivity are… read more here.
Keywords: functionalized enyl; nitro functionalized; enyl pyrrolidones; three component ... See more keywords
Visible-Light-Mediated Three-Component Radical Iodosulfonylative Cyclization of Enynes.
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DOI: 10.1021/acs.orglett.2c00655
Abstract: An efficient three-component radical iodosulfonylative cyclization of enynes is described. The visible-light irradiation of iodoform with sulfinates enables sulfonyl radical generation under catalyst- and oxidant-free conditions and triggers the radical addition, cyclization and iodination cascade… read more here.
Keywords: iodosulfonylative cyclization; cyclization enynes; radical iodosulfonylative; three component ... See more keywords
Four-Component Radical Dual Difunctionalization (RDD) of Two Different Alkenes with Aldehydes and tert-Butyl Hydroperoxide (TBHP): An Easy Access to β,δ-Functionalized Ketones.
Sign Up to like & getrecommendations! Published in 2019 at "Organic letters"
DOI: 10.1021/acs.orglett.9b02264
Abstract: A convenient Fe-catalyzed four-component radical dual difunctionalization and ordered assembly of two alkenes with aromatic/aliphatic aldehydes and TBHP to provide chain elongated β,δ-functionalized ketones via a one-pot procedure has been developed. Aldehydes were homolytically cleavaged… read more here.
Keywords: four component; radical dual; dual difunctionalization; functionalized ketones ... See more keywords
Asymmetric Three-Component Radical Alkene Carboazidation by Direct Activation of Aliphatic C-H Bonds.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c02012
Abstract: Azide compounds are widely present in natural products and drug molecules, and their easy-to-transform characteristics make them widely used in the field of organic synthesis. The merging of transition-metal catalysis with radical chemistry offers a… read more here.
Keywords: carboazidation; activation aliphatic; three component; direct activation ... See more keywords
Additive-Free Four-Component Radical Selenosulfonylation of Alkenes
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DOI: 10.1039/d5qo00812c
Abstract: While multicomponent tandem reactions offer an efficient platform for the difunctionalization of alkenes, the precise regulation of component ordering in reaction systems remains a persistent challenge. Herein, we present an... read more here.
Keywords: free four; component; four component; radical selenosulfonylation ... See more keywords