Nickel-Catalyzed Three-Component Reductive Alkylacylation of Electron-Deficient Activated Alkenes.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c03210
Abstract: Herein, we present a nickel-catalyzed three-component reductive alkylacylation of electron-deficient activated alkenes with tertiary alkyl bromides and acid anhydrides. This method enables the efficient preparation of a variety of ketones with broad substrate scope and… read more here.
Keywords: alkylacylation electron; catalyzed three; component reductive; three component ... See more keywords
Electricity-driven three-component reductive coupling reaction for the synthesis of diarylmethylamine.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc05330f
Abstract: A three-component reductive coupling reaction of aldehydes, amines and cyanopyridines under electrochemical conditions has been developed. The in situ generated imine and cyanopyridine simultaneously undergo single-electron reduction at the cathode, and afford diarylmethylamines through radical… read more here.
Keywords: electricity driven; coupling reaction; reductive coupling; component reductive ... See more keywords
Three-component reductive conjugate addition/aldol tandem reaction enabled by nickel/photoredox dual catalysis
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d2sc06303d
Abstract: A three-component reductive cross-coupling of aryl halides, aldehydes, and alkenes by nickel/photoredox dual catalysis is disclosed. The key to success for this tandem transformation is to identify α-silylamine as a unique organic reductant, which releases… read more here.
Keywords: conjugate addition; component reductive; dual catalysis; photoredox dual ... See more keywords