A one-pot and three-component synthetic approach for the preparation of asymmetric and multi-substituted 1,4-dihydropyrazines
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DOI: 10.1016/j.tetlet.2019.151257
Abstract: Abstract An efficient, one-pot and three-component synthesis of a new series of 2-acyl-3,4,6-triaryl-1,4-dihydropyrazines is described. This two-step strategy involves treatment of phenacyl bromides and anilines to give the nucleophilic substitution intermediate followed by Michael-addition-cyclization to… read more here.
Keywords: pot three; three component; component synthetic; one pot ... See more keywords