The functionality of telomerase depends on CPF–CF induced 3′end processing of its RNA component TLC1 and a novel Nrd1–Nab3 surveillance mechanism
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DOI: 10.1093/nar/gkaf480
Abstract: Abstract Telomere elongation is driven by telomerase, which consists of several proteins and the ncRNA component TLC1 in yeast. While many ncRNAs are terminated via the Nrd1–Nab3–Sen1 (NNS) pathway, we found that TLC1 requires cleavage… read more here.
Keywords: nrd1 nab3; end processing; cpf; component tlc1 ... See more keywords