Components of the choline oxidation pathway modify the association between the apolipoprotein ε4 gene variant and cognitive decline in patients with dementia
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DOI: 10.1016/j.brainres.2019.146519
Abstract: BACKGROUND Metabolites involved in one-carbon metabolism (OCM) may predict cognitive prognosis in dementia. The link between OCM, apolipoprotein E (APOE), and DNA methylation creates a biologically plausible mechanism of interaction. AIM To assess OCM metabolites… read more here.
Keywords: cognitive prognosis; components choline; decline; patients dementia ... See more keywords