UBA6 and NDFIP1 regulate the degradation of ferroportin.
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DOI: 10.3324/haematol.2021.278530
Abstract: Hepcidin regulates iron homeostasis by controlling the level of ferroportin, the only membrane channel that facilitates export of iron from within cells. Binding of hepcidin to ferroportin induces the ubiquitination of ferroportin at multiple lysine… read more here.
Keywords: degradation; components ubiquitin; ferroportin; hepcidin ... See more keywords