Articles with "composite scaffold" as a keyword



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Biomimetic Hydrogels Loaded with Nanofibers Mediate Sustained Release of pDNA and Promote In Situ Bone Regeneration.

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Published in 2021 at "Macromolecular bioscience"

DOI: 10.1002/mabi.202000393

Abstract: Polymer hydrogels are generally insufficient biomechanics, strong resistance to cell adhesion, and weak bioactivity which limits their application in bone tissue engineering considerably. In order to develop a bone tissue engineering material with both good… read more here.

Keywords: bone; composite scaffold; sustained release; bone regeneration ... See more keywords
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Preparation of a biphase composite scaffold and its application in tissue engineering for femoral osteochondral defects in rabbits

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Published in 2017 at "International Orthopaedics"

DOI: 10.1007/s00264-017-3522-2

Abstract: PurposeThree-dimensional bioactive scaffolds are useful tools for stem cell implant in tissue-engineering. For chondral and subchondral repair, the chondroinductive and osteoinductive property of a scaffold is a major challenge. The scaffolds that aim to osteogenic… read more here.

Keywords: biphase composite; composite scaffold; biphase; tissue engineering ... See more keywords
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Porous composite scaffold incorporating osteogenic phytomolecule icariin for promoting skeletal regeneration in challenging osteonecrotic bone in rabbits.

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Published in 2018 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2017.10.025

Abstract: Steroid-associated osteonecrosis (SAON) often requires surgical core decompression (CD) in the early stage for removal of necrotic bone to facilitate repair where bone grafts are needed for filling bone defect and avoiding subsequent joint collapse.… read more here.

Keywords: pti scaffold; composite scaffold; icariin; scaffold ... See more keywords

PLGA/β-TCP composite scaffold incorporating salvianolic acid B promotes bone fusion by angiogenesis and osteogenesis in a rat spinal fusion model.

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Published in 2019 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2018.04.004

Abstract: Spinal disorders often require surgical treatment called spinal fusion to restore a stabilized spine where bone grafts are implanted for the fusion of adjacent vertebras. In this study, we developed a bioactive composite scaffold incorporated… read more here.

Keywords: spinal fusion; composite scaffold; angiogenesis; fusion ... See more keywords

Electroactive composite scaffold with locally expressed osteoinductive factor for synergistic bone repair upon electrical stimulation.

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Published in 2019 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2019.119617

Abstract: Tissue engineering is a promising strategy for the repair of large-scale bone defects, in which scaffolds and growth factors are two critical issues influencing the efficacy of bone regeneration. Unfortunately, the broad application of growth… read more here.

Keywords: phbmp; composite scaffold; upon electrical; electrical stimulation ... See more keywords
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Synthesis and characterization of gelatin-PVP polymer composite scaffold for potential application in bone tissue engineering

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Published in 2019 at "European Polymer Journal"

DOI: 10.1016/j.eurpolymj.2019.07.007

Abstract: Abstract An ideal scaffold which mimics extracellular matrix as an artificial bone graft substitute is the need of current clinical management of orthopaedic complications. In this study, a porous biomimetic scaffold was synthesized using in… read more here.

Keywords: gelatin pvp; composite scaffold; polymer composite; polymer ... See more keywords
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Preparation and properties of calcium phosphate cement/small intestinal submucosa composite scaffold mimicking bone components and Haversian microstructure

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Published in 2018 at "Materials Letters"

DOI: 10.1016/j.matlet.2017.10.065

Abstract: Abstract Calcium phosphate cement (CPC)/small intestinal submucosa (SIS) composite scaffold was prepared in this work by subtly stacking bio-inspired Haversian motifs (lamellar cylindrical motifs), which can form a structure similar to the Haversian microstructure in… read more here.

Keywords: calcium phosphate; composite scaffold; small intestinal; phosphate cement ... See more keywords
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Development of functionally graded porous titanium/silk fibroin composite scaffold for bone repair

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Published in 2021 at "Materials Letters"

DOI: 10.1016/j.matlet.2020.128670

Abstract: Abstract A composite scaffold comprising a silk fibroin (SF) sponge on functionally graded titanium (FG-Ti) was developed. The FG-Ti showed a radial graded structure similar to native long bone and better mechanical properties than those… read more here.

Keywords: functionally graded; composite scaffold; silk fibroin; titanium ... See more keywords
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Development of Cellulose Nanofibril/Casein-Based 3D Composite Hemostasis Scaffold for Potential Wound-Healing Application.

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Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.1c21039

Abstract: Excessive bleeding in traumatic hemorrhage is the primary concern for natural wound healing and the main reason for trauma deaths. The three-dimensional (3D) bioprinting of bioinks offers the desired structural complexity vital for hemostasis activity… read more here.

Keywords: wound healing; hemostasis; composite scaffold; spectroscopy ... See more keywords
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Hierarchically Porous Composite Scaffold Composed of SBA-15 Microrods and Reduced Graphene Oxide Functionalized with Cyclodextrin for Water Purification.

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Published in 2019 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.9b01845

Abstract: Large-scale decontamination of bisphenol A (BPA) from wastewater under field conditions is an urgent need because of the harmful toxic effects of BPA on living organisms. In this study, we report the fabrication of a… read more here.

Keywords: composite scaffold; scaffold composed; porous composite; scaffold ... See more keywords
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Chitosan-vancomycin hydrogel incorporated bone repair scaffold based on staggered orthogonal structure: a viable dually controlled drug delivery system

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Published in 2023 at "RSC Advances"

DOI: 10.1039/d2ra07828g

Abstract: In clinical practice, challenges remain in the treatment of large infected bone defects. Bone tissue engineering scaffolds with good mechanical properties and antibiotic-controlled release are powerful strategies for infection treatment. In this study, we prepared… read more here.

Keywords: system; van; hydrogel; composite scaffold ... See more keywords