Disease association and comparative genomics of compositional bias in human proteins.
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DOI: 10.12688/f1000research.129929.2
Abstract: Background: The evolutionary rate of disordered protein regions varies greatly due to the lack of structural constraints. So far, few studies have investigated the presence/absence patterns of compositional bias, indicative of disorder, across phylogenies in… read more here.
Keywords: human proteins; disease; disease association; compositional bias ... See more keywords
Compositional Bias of Intrinsically Disordered Proteins and Regions and Their Predictions
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DOI: 10.3390/biom12070888
Abstract: Intrinsically disordered regions (IDRs) carry out many cellular functions and vary in length and placement in protein sequences. This diversity leads to variations in the underlying compositional biases, which were demonstrated for the short vs.… read more here.
Keywords: compositional bias; intrinsically disordered; disordered proteins; idrs ... See more keywords