Articles with "compound" as a keyword



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A Two-Pathway Model for the Evolution of Colloidal Compound Semiconductor Quantum Dots and Magic-Size Clusters.

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Published in 2022 at "Advanced materials"

DOI: 10.1002/adma.202107940

Abstract: A fundamental understanding of formation pathways is critical to the controlled synthesis of colloidal semiconductor nanocrystals. As ultrasmall-size quantum dots (QDs) sometimes emerge in reactions along with magic-size clusters (MSCs), distinguishing their individual pathway of… read more here.

Keywords: size; pathway model; compound; evolution ... See more keywords
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A Switchable One‐Compound Diode

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Published in 2022 at "Advanced Materials"

DOI: 10.1002/adma.202208698

Abstract: A diode requires the combination of p‐ and n‐type semiconductors or at least the defined formation of such areas within a given compound. This is a prerequisite for any IT application, energy conversion technology, and… read more here.

Keywords: diode; compound; switchable one; pnp switching ... See more keywords
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Synthesis, biological evaluation, and docking studies of some 5‐chloro‐2(3H)‐benzoxazolone Mannich bases derivatives as cholinesterase inhibitors

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Published in 2018 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.201700273

Abstract: A series of N‐substituted‐5‐chloro‐2(3H)‐benzoxazolone derivatives were synthesized and evaluated for their acetylcholinesterase (AChE), butyrylcholinesterase (BuChE) inhibitory, and antioxidant activities. The structures of the title compounds were confirmed by spectral and elemental analyses. The cholinesterase (ChE)… read more here.

Keywords: ache; chloro benzoxazolone; compound; synthesis biological ... See more keywords
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Design, synthesis, biological evaluations, molecular docking, and in vivo studies of novel phthalimide analogs

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Published in 2018 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.201700363

Abstract: A series of novel phthalimide analogs containing an indole or brominated indole moiety were synthesized and their antimicrobial activity was evaluated. Compound 8 showed a broad spectrum activity, revealing 53–67% of erythromycin activity on the… read more here.

Keywords: design synthesis; novel phthalimide; cell lines; compound ... See more keywords
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New [1,2,4]triazolo[4,3‐c]quinazoline derivatives as vascular endothelial growth factor receptor‐2 inhibitors and apoptosis inducers: Design, synthesis, docking, and antiproliferative evaluation

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Published in 2022 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202200133

Abstract: In continuation of our previous efforts in the field of design and synthesis of vascular endothelial growth factor receptor (VEGFR)‐2 inhibitors, a new series of [1,2,4]triazolo[4,3‐c]quinazoline derivatives were designed and synthesized as modified analogs of… read more here.

Keywords: design synthesis; compound; endothelial growth; factor receptor ... See more keywords
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New quinazolinone‐based derivatives as DHFR/EGFR‐TK inhibitors: Synthesis, molecular modeling simulations, and anticancer activity

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Published in 2022 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202200417

Abstract: New 2‐mercapto‐quinazolin‐4‐one analogs were synthesized and tested for their in vitro anticancer activity, dihydrofolate reductase (DHFR) inhibition, and epidermal growth factor tyrosine kinase (EGFR‐TK) inhibition activities. Compound 24, which is characterized by a 2‐benzyl‐thio function,… read more here.

Keywords: compound; anticancer activity; inhibition; molecular modeling ... See more keywords
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Design, synthesis, and biological evaluation of a potent PLK4 inhibitor WY29 with 1H‐pyrazolo[3,4‐d]pyrimidine scaffold

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Published in 2022 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.202200490

Abstract: Centriole duplication occurs once per cell cycle and is regulated by Polo‐like kinase 4 (PLK4). Overexpression of PLK4 in somatic cells can lead to the excessive formation of centrioles, directly causing chromosome segregation errors and… read more here.

Keywords: compound; wy29; pyrazolo pyrimidine; plk4 ... See more keywords
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An Organogold Compound as Potential Antimicrobial Agent against Drug‐Resistant Bacteria: Initial Mechanistic Insights

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Published in 2021 at "Chemmedchem"

DOI: 10.1002/cmdc.202100342

Abstract: The rise of antimicrobial resistance has necessitated novel strategies to efficiently combat pathogenic bacteria. Metal‐based compounds have been proven as a possible alternative to classical organic drugs. Here, we have assessed the antibacterial activity of… read more here.

Keywords: drug; drug resistant; compound; organogold compound ... See more keywords
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A Zn(II)‐Containing Coordination Polymer: Synthesis, Crystal Structure and pH Fluorescent Sensing

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Published in 2017 at "Crystal Research and Technology"

DOI: 10.1002/crat.201700105

Abstract: In this work, a Zn(II)-containing coordination polymer, [Zn2(2,4′-tmbpt)2(o-bdc)2]·5H2O (1) [2,4′-tmbpt = 1-((1H-1,2,4-triazol-1-yl)methyl)-3-(4-pyridyl)-5-(2-pyridyl)-1,2,4-triazole and o-H2bdc = 1,2-benzenedicarboxylic acid] has been synthesized hydrothermally. The structure of the compound has been characterized by single crystal X-ray crystallography, elemental… read more here.

Keywords: containing coordination; coordination polymer; compound; structure ... See more keywords
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Accessing the primary SEI on lithium metal - A method for low concentrated compound analysis.

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Published in 2023 at "ChemSusChem"

DOI: 10.1002/cssc.202201912

Abstract: Despite large research efforts in the fields of lithium ion and lithium metal batteries there are still unanswered questions. One of them is the formation of the SEI in lithium-metal-anode-based battery systems. Until now, a… read more here.

Keywords: compound; sei lithium; lithium; analysis ... See more keywords
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Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone-based derivatives as DHFR inhibitors.

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Published in 2023 at "Drug development research"

DOI: 10.1002/ddr.22060

Abstract: Two series of quinazolinone derivatives were designed and synthesized as dihydrofolate reductase (DHFR) inhibitors. All compounds were evaluated for their antibacterial and antitumor activities. Antibacterial activity was evaluated against three strains of Gram-positive and Gram-negative… read more here.

Keywords: quinazolinone; compound; ccrf cem; activity ... See more keywords