A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction
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DOI: 10.1007/s10637-019-00818-z
Abstract: The bromodomain and extra-terminal domain (BET) family of proteins, especially bromodomain-containing protein 4 (BRD4), has emerged as exciting anti-tumor targets due to their important roles in epigenetic regulation. Therefore, the discovery of BET inhibitors with… read more here.
Keywords: compound 171; apoptosis; bet; anti tumor ... See more keywords