In Silico Exploration of Novel Tubulin Inhibitors: A Combination of Docking and Molecular Dynamics Simulations, Pharmacophore Modeling, and Virtual Screening
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DOI: 10.1155/2022/4004068
Abstract: Microtubules play a critical role in mitosis and cell division and are regarded as an excellent target for anticancer therapy. Although microtubule-targeting agents have been widely used in the clinical treatment of different human cancers,… read more here.
Keywords: tubulin inhibitors; molecular dynamics; pharmacophore model; docking molecular ... See more keywords