A preliminary metabolites identification of a novel compound with β-adrenolytic activity
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DOI: 10.1007/s43440-021-00273-9
Abstract: Background The identification of main metabolites and assessment of renal excretion of a novel compound with β-adrenolytic activity (2RS)-1-(1H-indol-4-yloxy)-3-((2-(2-methoxyphenoxy)ethyl)amino)propan-2-ol, briefly called (RS)-9 or 2F109, were studied in vivo in rat serum, urine, faeces, liver, intestine,… read more here.
Keywords: compound adrenolytic; mass; novel compound; compound ... See more keywords
HBK-10, A Compound with α1-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats
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DOI: 10.3390/ph15101256
Abstract: Arrhythmia, an irregular heartbeat, might be a life-threatening condition but also a risk factor for stroke or worsen the prognosis after myocardial infarction. The limited efficacy and proarrhythmic potential of the available drugs require searching… read more here.
Keywords: properties showed; compound adrenolytic; adrenolytic properties; antiarrhythmic hypotensive ... See more keywords