Oxazole-based compounds as anticancer agents.
Sign Up to like & getrecommendations! Published in 2018 at "Current medicinal chemistry"
DOI: 10.2174/0929867326666181203130402
Abstract: Heterocyclic compounds represent a significant target for anti-cancer research and drug discovery, due to their structural and chemical diversity. Oxazoles, with oxygen and nitrogen atoms present in the core structure, enable various type of interactions… read more here.
Keywords: compounds anticancer; anticancer agents; chemistry; oxazole based ... See more keywords
Metal-organic Compounds as Anticancer Agents: Versatile Building Blocks for Selective Action on G-quadruplexes.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220606160209
Abstract: BACKGROUND Since the 1980s, cancer research has focused primarily on developing new therapeutic agents targeting DNA alterations rather than understanding cancer as an integrated system composed of several modules. In this sense, G-quadruplex (G4) nucleic… read more here.
Keywords: organic compounds; compounds anticancer; anticancer agents; metal organic ... See more keywords
Bis-triazole-containing compounds with anticancer potential: A short review.
Sign Up to like & getrecommendations! Published in 2021 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026621666210728154728
Abstract: The development of novel anticancer agents with high efficiency is of great importance due to the severe anticancer scenario of the currently used drugs. Dimerization is a useful method to develop new drug candidates with… read more here.
Keywords: compounds anticancer; containing compounds; bis triazole; triazole containing ... See more keywords
Dietary Phenolic Compounds as Anticancer Natural Drugs: Recent Update on Molecular Mechanisms and Clinical Trials
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DOI: 10.3390/foods11213323
Abstract: Given the stochastic complexity of cancer diseases, the development of chemotherapeutic drugs is almost limited by problems of selectivity and side effects. Furthermore, an increasing number of protective approaches have been recently considered as the… read more here.
Keywords: anticancer natural; clinical trials; compounds anticancer; natural drugs ... See more keywords