Toward Understanding the Cold, Hot, and Neutral Nature of Chinese Medicines Using in Silico Mode-of-Action Analysis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.6b00725
Abstract: One important, however, poorly understood, concept of Traditional Chinese Medicine (TCM) is that of hot, cold, and neutral nature of its bioactive principles. To advance the field, in this study, we analyzed compound-nature pairs from… read more here.
Keywords: medicine; neutral nature; compounds associated; nature ... See more keywords
Plasma Advanced Glycation Endproducts and Dicarbonyl Compounds Are Not Associated with Coronary Atherosclerosis in Athletes.
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DOI: 10.1249/mss.0000000000003152
Abstract: ABSTRACT Purpose Coronary atherosclerosis is the leading cause of sudden death among athletes >35 yr old, but current cardiovascular risk prediction algorithms have not been validated for athletes. Advanced glycation end products (AGE) and dicarbonyl… read more here.
Keywords: compounds associated; age dicarbonyl; age; atherosclerosis ... See more keywords
Hit Compounds and Associated Targets in Intracellular Mycobacterium tuberculosis
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DOI: 10.3390/molecules27144446
Abstract: Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, is one of the most devastating infectious agents in the world. Chemical-genetic characterization through in vitro evolution combined with whole genome sequencing analysis was used identify novel… read more here.
Keywords: mycobacterium tuberculosis; tuberculosis; compounds associated; hit compounds ... See more keywords