KCa3.1 Channel Modulators as Potential Therapeutic Compounds for Glioblastoma
Sign Up to like & getrecommendations! Published in 2018 at "Current Neuropharmacology"
DOI: 10.2174/1570159x15666170630164226
Abstract: Background The intermediate-conductance Ca2+-activated K+ channel KCa3.1 is widely expressed in cells of the immune system such as T- and B-lymphocytes, mast cells, macrophages and microglia, but also found in dedifferentiated vascular smooth muscle cells,… read more here.
Keywords: channel modulators; kca3 channel; compounds glioblastoma; therapeutic compounds ... See more keywords
Natural Compounds in Glioblastoma Therapy: Preclinical Insights, Mechanistic Pathways, and Outlook
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DOI: 10.3390/cancers13102317
Abstract: Simple Summary Glioblastoma (GBM) is a tumor of the brain or spinal cord with poor clinical prognosis. Current interventions, such as chemotherapy and surgical tumor resection, are constrained by tumor invasion and cancer drug resistance.… read more here.
Keywords: natural compounds; gbm; compounds glioblastoma; glioblastoma therapy ... See more keywords