Novel Tricyclic Compounds as KRAS Inhibitors for Treating Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.3c00140
Abstract: Provided herein are novel tricyclic compounds as KRAS inhibitors, pharmaceutical compositions, use of such compounds in treating cancer and processes for preparing such compounds. read more here.
Keywords: kras inhibitors; novel tricyclic; treating cancer; tricyclic compounds ... See more keywords
Novel Pyrido[4,3‑d]pyrimidine Compounds as KRAS Inhibitors.
Sign Up to like & getrecommendations! Published in 2025 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.5c00493
Abstract: This highlight describes novel substituted pyrido-[4,3-d]-pyrimidine compounds as KRAS (Kirsten rat sarcoma viral oncogene homologue) inhibitors. The invention provides details about novel pyrido-[4,3-d]-pyrimidine compounds, their pharmaceutical composition, potential use, and treatment for KRAS-related diseases, such… read more here.
Keywords: novel pyrido; compounds kras; kras inhibitors; pyrido pyrimidine ... See more keywords