Synthesis and Evaluation of Novel DNA Minor Groove Binders as Antiamoebic Agents
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DOI: 10.3390/antibiotics11070935
Abstract: The free-living amoeba Acanthamoeba castellanii is responsible for the central nervous infection granulomatous amoebic encephalitis and sight-threatening infection Acanthamoeba keratitis. Moreover, no effective treatment is currently present, and a combination drug therapy is used. In… read more here.
Keywords: compounds mgb3; minor groove; groove binders; dna minor ... See more keywords