Articles with "compounds orexin" as a keyword



Novel Urea-Containing Compounds as Orexin Receptor Agonists for Treating Sleep Disorders, Namely, Narcolepsy, Hypersomnia, and Sleep Apnea Syndrome.

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Published in 2025 at "ACS medicinal chemistry letters"

DOI: 10.1021/acsmedchemlett.5c00067

Abstract: Provided herein are novel urea-containing compounds as orexin receptor agonists, pharmaceutical compositions, use of such compounds in treating sleep disorders, namely, narcolepsy, hypersomnia, and sleep apnea syndrome as well as processes for preparing such compounds. read more here.

Keywords: compounds orexin; containing compounds; receptor agonists; novel urea ... See more keywords