Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers
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DOI: 10.1007/s00204-020-02811-5
Abstract: A library of 14 mono-oxime quinuclidinium-based compounds with alkyl or benzyl substituent were synthesized and characterized in vitro as potential antidotes for organophosphorus compounds (OP) poisoning treatment. We evaluated their potency for reversible inhibition and… read more here.
Keywords: butyrylcholinesterase; organophosphorus compounds; based bioscavengers; quinuclidinium ... See more keywords