Nectar antimicrobial compounds and their potential effects on pollinators.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in insect science"
DOI: 10.1016/j.cois.2021.03.004
Abstract: Nectar is a sugary, aqueous solution that plants offer as a reward to animal mutualists for visitation. Since nectars are so nutrient-rich, they often harbor significant microbial communities, which can be pathogenic, benign, or even… read more here.
Keywords: antimicrobial compounds; compounds potential; nectar antimicrobial; chemistry ... See more keywords
Hexahydropyrrolo[2,3-b]indole compounds as potential therapeutics for Alzheimer Disease.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.9b00297
Abstract: Alzheimer's disease (AD) is the most common form of dementia among the elderly and has become a leading public health concern worldwide. It represents a huge economic and psychological burden to caregivers and families. The… read more here.
Keywords: compounds potential; alzheimer disease; potential therapeutics; indole compounds ... See more keywords
Natural Antioxidant Compounds as Potential Pharmaceutical Tools against Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c03291
Abstract: Natural antioxidants are a very large diversified family of molecules classified by activity (enzymatic or nonenzymatic), chemical-physical properties (e.g., hydrophilic or lipophilic), and chemical structure (e.g., vitamins, polyphenols, etc.). Research on natural antioxidants in various… read more here.
Keywords: pharmaceutical tools; compounds potential; natural antioxidant; potential pharmaceutical ... See more keywords
C-H deuteration of organic compounds and potential drug candidates.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d0cs01496f
Abstract: C-H deuteration has been intricately developed to satisfy the urgent need for site-selectively deuterated organic frameworks. Deuteration has been primarily used to study kinetic isotope effects of reactions but recently its significance in pharmaceutical chemistry… read more here.
Keywords: compounds potential; deuteration; potential drug; organic compounds ... See more keywords
Halophytes as source of bioactive phenolic compounds and their potential applications.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2021.1959295
Abstract: Halophytes are salt-tolerant plants that inhabit environments in which they are exposed to extreme stress, wherefore they exhibit conserved and divergent metabolic responses different from those of conventional plants. Thus, the synthesis and accumulation of… read more here.
Keywords: bioactive phenolic; halophytes source; compounds potential; source bioactive ... See more keywords
Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14816
Abstract: Traditional chemotherapy is being considered due to hindrances caused by systemic toxicity. Currently, the administration of multiple chemotherapeutic drugs with different biochemical/molecular targets, known as combination chemotherapy, has attained numerous benefits like efficacy enhancement and… read more here.
Keywords: natural compounds; compounds potential; evidence; cancer ... See more keywords
Design and development of macrocyclization methods for compounds with potential tuberculocidal activity to decrease CYP450 liver cytochrome inhibition
Sign Up to like & getrecommendations! Published in 2017 at "Russian Journal of General Chemistry"
DOI: 10.1134/s1070363217040107
Abstract: A procedure for macrocyclization of compounds with potential tuberculocidal activity was developed in order to obtaining compounds with a lower degree of inhibition of the key CYP 3A4 cytochrome. read more here.
Keywords: tuberculocidal activity; potential tuberculocidal; compounds potential; macrocyclization ... See more keywords
Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.698192
Abstract: The neurofibromatosis syndromes, including NF1, NF2, and schwannomatosis, are tumor suppressor syndromes characterized by multiple nervous system tumors, particularly Schwann cell neoplasms. NF-related tumors are mainly treated by surgery, and some of them have been… read more here.
Keywords: natural compounds; compounds potential; molecular pathogenesis; pathogenesis natural ... See more keywords
Bioactive natural compounds as potential medications for osteogenic effects in a molecular docking approach
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.955983
Abstract: Bone defect repair and fracture healing are critical challenges in clinical treatments. Bioactive natural compounds are potential resources for medications for osteogenic effects. We have identified icariin, the effective ingredient of Epimedium pubescens, to promote… read more here.
Keywords: compounds potential; medications osteogenic; natural compounds; bone ... See more keywords
Natural Compounds: Potential Therapeutics for the Inhibition of Cartilage Matrix Degradation in Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life13010102
Abstract: Osteoarthritis (OA) is the most common degenerative joint disease characterized by enzymatic degradation of the cartilage extracellular matrix (ECM) causing joint pain and disability. There is no disease-modifying drug available for the treatment of OA.… read more here.
Keywords: compounds potential; natural compounds; cartilage; degradation ... See more keywords
Phytoprogestins: Unexplored Food Compounds with Potential Preventive and Therapeutic Effects in Female Diseases
Sign Up to like & getrecommendations! Published in 2021 at "Nutrients"
DOI: 10.3390/nu13124326
Abstract: In recent years, there has been an increasing interest in natural therapies to prevent or treat female diseases. In particular, many studies have focused on searching natural compounds with less side effects than standard hormonal… read more here.
Keywords: food compounds; potential preventive; unexplored food; female diseases ... See more keywords